Cas number: 171599-83-0 Molecular Formula: C 2 2 H 3 0 N 6 O 4 S·C 6 H 8 O 7 = 666.70
| Melting Point | 49-53° |
| Density | 1.05 g/cm³ |
| storage temp | cool, dry place and avoid exposure to light or high temperature |
| solubility | easily soluble in ethanol, acetone, ether, benzene and methylene chloride, but insoluble in water |
| optical activity | [α]D20 = +61.0° (ethanol solution) |
| Appearance | white to light yellow crystalline powder |
During sexual stimulation, the parasympathetic nerve, non adrenergic and non cholinergic nerve (NANC) endings and vascular endothelial cells release nitric oxide (NO) under the action of nitric oxide synthase (NOS). In the blood vessels, the soluble guanylate cyclase (sGC) is usually activated by NO, and sGC acts on guanosine triphosphate to produce cGMP. The cGMP in the corpus cavernosum of the penis exerts a strong vasodilator effect by reducing the concentration of Ca2+in the smooth muscle cells of the corpus cavernosum, causing relaxation of the smooth muscle cells and an increase in blood flow within the corpus cavernosum, leading to an erection. Jinyang alkali reduces the degree of degradation of cGMP, thereby preserving the relaxing effect of cGMP on the corpus cavernosum of the penis and causing penile erection. In vivo, cGMP is degraded and inactivated by PDE5.
Suitable for treating erectile dysfunction (ED) of the penis, it is effective for erectile dysfunction caused by the use of antidepressants, antipsychotics, and antihypertensive drugs, as well as for erectile dysfunction caused by surgery or trauma
It can be made into tablets, pills, hard capsules, soft capsules, and can be used as medicinal wine, oral liquid, coffee, granules, chewable tablets, lozenges, chewing gum, and other dosage forms. For adults, the dosage should be 10-100mg per day, which can be increased or decreased according to the user's situation. It is better to take it on an empty stomach (especially avoid taking it with high fat food), and do not drink alcohol before use Tea (taking should not be consumed at the same time, which does not mean that drinking alcohol at the same time can seriously reduce the erectile function of).
Effective time: Most people take it for one hour to take effect. It is recommended to take medication about 1 hour before sexual intercourse, with its effects lasting for 48 to 72 hours, and some may last for 116 hours.
